TY - JOUR PY - 2021// TI - Antenatal depressive symptoms in Kenyan women living with HIV: contributions of recent HIV diagnosis, stigma, and partner violence JO - AIDS care A1 - Osborn, Lusi A1 - Ronen, Keshet A1 - Larsen, Anna M. A1 - Richardson, Barbra A1 - Khasimwa, Brian A1 - Chohan, Bhavna A1 - Matemo, Daniel A1 - Unger, Jennifer A1 - Drake, Alison L. A1 - Kinuthia, John A1 - John-Stewart, Grace SP - ePub EP - ePub VL - ePub IS - ePub N2 - Depression among pregnant women living with HIV (WLWH) in sub-Saharan Africa leads to poor pregnancy and HIV outcomes. This cross-sectional analysis utilized enrollment data from a randomized trial (Mobile WAChX, NCT02400671) in six Kenyan public maternal and child health clinics. Depressive symptoms were assessed with the Patient Health Questionnaire-9 (PHQ-9), stigma with the Stigma Scale for Chronic Illness, and intimate partner violence (IPV) with the Abuse Assessment Screen. Correlates of moderate-to-severe depressive symptoms ("depression", PHQ-9 score ≥10) were assessed using generalized estimating equation models clustered by facility. Among 824 pregnant WLWH, 9% had depression; these women had more recent HIV diagnosis than those without depression (median 0.4 vs. 2.0 years since diagnosis, p = .008). Depression was associated with HIV-related stigma (adjusted Prevalence Ratio [aPR]:2.36, p = .025), IPV (aPR:2.93, p = .002), and lower social support score (aPR:0.99, p = .023). Using population-attributable risk percent to estimate contributors to maternal depression, 81% were attributable to stigma (27%), recent diagnosis (24%), and IPV (20%). Integrating depression screening and treatment in prevention of mother-to-child HIV transmission programs may be beneficial, particularly in women recently diagnosed or reporting stigma and IPV.

Language: en

LA - en SN - 0954-0121 UR - http://dx.doi.org/10.1080/09540121.2021.1981216 ID - ref1 ER -