TY - JOUR PY - 2021// TI - Simulated driving in the epilepsy monitoring unit: effects of seizure type, consciousness, and motor impairment JO - Epilepsia A1 - Kumar, Avisha A1 - Martin, Reese A1 - Chen, William A1 - Bauerschmidt, Andrew A1 - Youngblood, Mark W. A1 - Cunningham, Courtney A1 - Si, Yang A1 - Ezeani, Cel A1 - Kratochvil, Zachary A1 - Bronen, Jared A1 - Thomson, James A1 - Riordan, Katherine A1 - Yoo, Ji Yeoun A1 - Shirka, Romina A1 - Manganas, Louis A1 - Krestel, Heinz A1 - Hirsch, Lawrence J. A1 - Blumenfeld, Hal SP - ePub EP - ePub VL - ePub IS - ePub N2 - People with epilepsy face serious driving restrictions, determined using retrospective studies. To relate seizure characteristics to driving impairment, we aimed to study driving behavior during seizures with a simulator. Patients in the Yale New Haven Hospital undergoing video-electroencephalographic monitoring used a laptop-based driving simulator during ictal events. Driving function was evaluated by video review and analyzed in relation to seizure type, impairment of consciousness/responsiveness, or motor impairment during seizures. Fifty-one seizures in 30 patients were studied. In terms of seizure type, we found that focal to bilateral tonic-clonic or myoclonic seizures (5/5) and focal seizures with impaired consciousness/responsiveness (11/11) always led to driving impairment; focal seizures with spared consciousness/responsiveness (0/10) and generalized nonmotor (generalized spike-wave bursts; 1/19) usually did not lead to driving impairment. Regardless of seizure type, we found that seizures with impaired consciousness (15/15) or with motor involvement (13/13) always led to impaired driving, but those with spared consciousness (0/20) or spared motor function (5/38) usually did not. These results suggest that seizure types with impaired consciousness/responsiveness and abnormal motor function contribute to impaired driving. Expanding this work in a larger cohort could further determine how results with a driving simulator may translate into real world driving safety.

Language: en

LA - en SN - 0013-9580 UR - http://dx.doi.org/10.1111/epi.17136 ID - ref1 ER -