TY  - JOUR
PY  - 2021//
TI  - Hospital volume-outcome relationship in severe traumatic brain injury: a nationwide observational study in Japan
JO  - World neurosurgery
A1  - Shibahashi, Keita
A1  - Hoda, Hidenori
A1  - Oishio, Masato
A1  - Okura, Yoshihiro
A1  - Sugiyama, Kazuhiro
A1  - Hamabe, Yuichi
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - OBJECTIVE: The hospital volume-outcome relationship in patients with severe traumatic brain injury (TBI) remains unclear. This study investigated the association between the volume of patients with severe TBI and in-hospital mortality. <br><br>METHODS: This observational study identified patients with severe TBI (Glasgow Coma Scale score < 9 and Abbreviated Injury Scale head score ≥ 3) from the Japan Trauma Databank (2010-2018). Hospitals were grouped based on the annual patient volume as follows: low-volume (4-19 patients/year); middle-volume (20-35 patients/year); and high-volume (36-51 patients/year) groups. The association between hospital volume categories and in-hospital mortality was examined using a multivariate mixed-effect logistic regression analysis. A subgroup analysis was performed based on the presence of severe extracranial injuries. <br><br>RESULTS: A total of 11,344 patients from 64 hospitals were included. The median age of the patients was 57 years (interquartile range, 40-77) and 7,933 (70.0%) patients were men. A total of 4,879 (43.1%) patients died in the hospital. The medium-volume (adjusted odds ratio [OR], 0.76; 95% confidence interval [CI], 0.62-0.93) and high-volume (adjusted OR, 0.69; 95% CI, 0.52-0.94) groups were significantly associated with lower in-hospital mortality. The subgroup analysis revealed that the medium-volume (adjusted OR, 0.70; 95% CI, 0.54-0.92) and high-volume (adjusted OR, 0.64; 95% CI, 0.42-0.96) groups were significantly associated with lower in-hospital mortality for isolated TBI patients. <br><br>CONCLUSIONS: Higher hospital volumes were significantly associated with lower in-hospital mortality after severe TBI. Regionalization and referral to higher-volume hospitals are beneficial for severe TBI patients.<p />  <p>Language: en</p>
LA  - en
SN  - 1878-8750
UR  - http://dx.doi.org/10.1016/j.wneu.2021.12.106
ID  - ref1
ER  -