TY  - JOUR
PY  - 2022//
TI  - Roles of alcohol use disorder and resilience in risk of suicide attempt in men: a Swedish population-based cohort
JO  - Suicide and life-threatening behavior
A1  - Lannoy, Séverine
A1  - Ohlsson, Henrik
A1  - Sundquist, Jan
A1  - Sundquist, Kristina
A1  - Edwards, Alexis C.
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - INTRODUCTION: Alcohol use disorder (AUD) has been identified as a strong risk factor for suicide attempt. However, few studies have considered protective factors that may moderate this association, such as resilience. <br><br>METHODS: We used longitudinal nationwide Swedish data of 903,333 males born 1960-1980 and 48,285 males born 1949-1951. We performed Cox proportional hazards models to test the role of AUD, resilience, and their interaction on risk for suicide attempt. We used co-relative models to account for familial factors. <br><br>RESULTS: Alcohol use disorder was strongly associated with increased risk of suicide attempt [hazard ratio (HR) = 12.22], while resilience was associated with reduced risk (HR = 0.73). Multiplicative interaction (HR = 1.21) showed that, in the context of AUD, the protective role of resilience on risk of suicide attempt was somewhat attenuated. Co-relative analyses supported both familial liability and a possible causal pathway between AUD, resilience, and suicide attempt. In the cohort born 1949-1951, resilience subcomponents-social maturity, interests, psychological energy, home conditions, and emotional control-were all associated with reduced suicide attempt risk (HRs between 0.63 and 0.74). <br><br>CONCLUSION: While resilience is associated with reduced risk of suicide attempt, this effect is less pronounced in the context of AUD. These associations are potentially causal.<p />  <p>Language: en</p>
LA  - en
SN  - 0363-0234
UR  - http://dx.doi.org/10.1111/sltb.12825
ID  - ref1
ER  -