TY - JOUR
PY - 2022//
TI - Walking speed and patient-reported outcomes in young adults with cerebral palsy
JO - Developmental medicine and child neurology
A1 - MacCarthy, Matthew
A1 - Heyn, Patricia
A1 - Tagawa, Alex
A1 - Carollo, James
SP - ePub
EP - ePub
VL - ePub
IS - ePub
N2 - AIM: To examine the relationship between quantitative gait measurements and self-reported physical, psychological, cognitive, and social function status in young adults with cerebral palsy (CP).
METHOD: Seventy-two adults with CP (range 18-48y; median age 23y [interquartile range 21-27y]; 34 males, 38 females), in Gross Motor Function Classification System levels I to IV, who previously underwent an instrumented gait analysis (IGA) at our center as children were recruited. Participants underwent a repeated IGA. National Institutes of Health Patient-Reported Outcomes Information System (PROMIS) instruments including the PROMIS-57, Applied Cognition - General Concerns (Short Form), and Applied Cognition - Executive Function (Short Form) were administered. Data derived from current and prior IGA were compared via non-parametric correlation analysis with PROMIS subscores.
RESULTS: Subscores for anxiety, depression, sleep, and fatigue did not significantly correlate with any IGA data. Walking speed, adjusted for stature, correlated strongly with multiple subscores: physical function (p<0.001, r(s) =0.708); participation in social roles (p=0.007, r(s) =0.319); executive function (p=0.005, r(s) =0.335). Pain interference correlated with longitudinal change in adjusted walking speed (p=0.032, r(s) =-0.259). The Applied Cognition - General Concerns (Short Form) correlated with prior absolute walking speed, but not adjusted values.
INTERPRETATION: This study underscores the importance of walking speed and its association with a variety of functional domains in adults with CP.
Language: en
LA - en SN - 0012-1622 UR - http://dx.doi.org/10.1111/dmcn.15225 ID - ref1 ER -