TY  - JOUR
PY  - 2022//
TI  - Gender differences in clinical characteristics of emergency department patients involving illicit drugs use with analytical confirmation
JO  - Journal of the Formosan Medical Association
A1  - Weng, Te-I.
A1  - Chen, Lian-Yu
A1  - Chen, Hsien-Yi
A1  - Yu, Jiun-Hao
A1  - Su, Yu-Jang
A1  - Liu, Sung-Wei
A1  - Tracy, Derek K.
A1  - Chen, Yen-Chia
A1  - Lin, Chih-Chuan
A1  - Fang, Cheng-Chung
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - BACKGROUND: To compare gender differences in socio-demographics, clinical manifestations, and laboratory test results of individuals who visited emergency departments (EDs) involving drug use. <br><br>METHODS: We retrospectively collected the data from 10 hospitals in Taiwan on drug-related ED visits from May 2017 to December 2020. We then examined the gender differences in their socio-demographics, clinical manifestations, urine toxicological results, and other laboratory tests results using chi-square or multivariable logistic regression. <br><br>RESULTS: Among individuals with drug-related ED visits, there were 546 (73.7%) men and 195 (26.3%) women. The most commonly used drugs were meth/amphetamine, followed by synthetic cathinones, and ketamine and its analogs. Compared to men, women were younger (32.03 ± 10.86 vs. 36.51 ± 10.84 years, p < 0.001) and more likely to use new psychoactive substances (NPS) (p = 0.011). Men were more likely to have human immunodeficiency virus infection (p < 0.001), whereas women were more likely to report psychiatric comorbidities (p = 0.003). Women were less likely to have aggressive behaviors (odds ratio (OR): 0.59, 95% CI: 0.39-0.88). After adjusting for socio-demographics and drug types, women were still less likely to have aggressive behaviors than men (adjusted OR: 0.59, 95% CI: 0.38-0.93). The likelihood of rhabdomyolysis and intensive care unit admission was higher in men (p < 0.001). <br><br>CONCLUSION: We found considerable gender differences in clinical characteristics among ED-visiting drug users, which could offer valuable information for the future development of more tailored gender-specific drug prevention and treatment strategies.<p />  <p>Language: en</p>
LA  - en
SN  - 0929-6646
UR  - http://dx.doi.org/10.1016/j.jfma.2022.03.007
ID  - ref1
ER  -