TY - JOUR
PY - 2022//
TI - Toxoplasma gondi infection and aggression in autistic children
JO - Pediatric infectious disease journal
A1 - Hamid, Najmeh
A1 - Azizy, Boshra
A1 - Hamidinejad, Hossein
SP - ePub
EP - ePub
VL - ePub
IS - ePub
N2 - BACKGROUND: Toxoplasmosis is an infectious disease caused by the obligatory intracellular parasite Toxoplasma gondii. The main aim of this study was to evaluate a possible relationship between aggression in autistic children with infection by T. gondii.
METHODS: The research design was an analytical (comparative) cross sectional study. The participants included (N = 100) subjects (50 autistic and 50 normal children) between 3 and 12 years old. They were matched for age, socioeconomic status, lack of physical and mental illness. The instruments were preschool aggression scale and enzyme-linked immunosorbent assay procedure to essay the blood sample test. Five milliliters of blood samples were collected to assess the presence of T. gondii infection.
RESULTS: The results showed that autistic children had a higher rate of infection by T. gondii than normal children. Furthermore, children infected with T. gondii were more aggressive than the noninfected group.
CONCLUSIONS: In autistic children, T. gondii infection was significantly higher than in the normal group. Also, autistic children who were infected with the parasite were more aggressive.
Language: en
LA - en SN - 0891-3668 UR - http://dx.doi.org/10.1097/INF.0000000000003516 ID - ref1 ER -