TY  - JOUR
PY  - 2022//
TI  - Magic potion, concoction, or poison? Multiorgan dysfunction syndrome and dicarboxylic aciduria after quack prescriptions [letter]
JO  - Indian journal of pediatrics
A1  - John, Elizabeth Mary
A1  - Kolisambeevi, Arif Abdulsalam
A1  - Pournami, Femitha
A1  - Prithvi, Ajai Kumar
A1  - Nandakumar, Anand
A1  - Prabhakar, Jyothi
A1  - Jain, Naveen
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - India faces myriad, inconceivable issues on the medical front. We received a critically ill young infant, with acute onset multiorgan dysfunction syndrome (MODS): encephalopathy, respiratory and hepatic failure, shock, and acute kidney injury. Differentials considered were sepsis (bacterial/viral), inborn errors of metabolism, hemophagocytosis, critical congenital heart disease, and endocrinopathies. To rule out these, investigations including polymerase chain reaction for pathogens and tandem mass spectrometry (TMS) were done but they did not conclusively support any of the above. Continued parent communication revealed history of oral/nasal instillation "therapy" with indigenous oil and plant-based concoctions for a minor cold.     Intensive care supports to combat organ damages included ventilation for lipoid pneumonia, antibiotics, inotropes, fluid management, and blood product transfusions. Urine gas chromatography (GC) revealed dicarboxylic aciduria. Albeit this would form a basis for considering organic academia; these molecules are found in large concentrations in rancid oils (including medium chain triglycerides) and plant products [1]. These red herrings may be taken into consideration by intensivists...<p />  <p>Language: en</p>
LA  - en
SN  - 0019-5456
UR  - http://dx.doi.org/10.1007/s12098-022-04242-9
ID  - ref1
ER  -