TY  - JOUR
PY  - 2022//
TI  - A rare case of a chemical burn: dithranol with salicylic acid
JO  - World journal of plastic surgery
A1  - Selva Raj, Dharshanan Raj
A1  - Adjei, Bismark
A1  - Al-Nahhas, Omar Farooq
A1  - Kamil, Lutfi
A1  - Yonjan, Indira
SP  - 138
EP  - 140
VL  - 11
IS  - 1
N2  - A 16-year-old female with psoriasis presented to our Plastic Surgery Department with a significant chemical burn to the neck, upper torso and left cheek (TBSA 6%). She applied a concoction of cream prescribed by her dermatologist in her native country, Poland when she returned to the United Kingdom. A few hours after application she developed a burn with pH of 5. A review of the cream revealed a mixture of 19% dithranol and 5% salicylic acid. This combination is recognized for managing psoriasis, however the strength of dithranol in the combination given is of a high concentration (normally <3%). This alone can cause a burn to the skin if left for a prolonged period of time. Salicylic acid is an enhancer which augments the stability of dithranol and increases its penetration and efficacy. The concentration of 5% is also on the higher end. Our patient was admitted for pain relief and further irrigation till normalization of the pH which was achieved after 3 days. A worrying aspect in our patients' case is that she was given the cream to commence at home. High concentration preparation is normally commenced in a controlled setting under medical supervision.<p />  <p>Language: en</p>
LA  - en
SN  - 2228-7914
UR  - http://dx.doi.org/10.52547/wjps.11.1.138
ID  - ref1
ER  -