TY  - JOUR
PY  - 2022//
TI  - Dandy-Walker malformation and intermittent explosive disorder: a case report
JO  - SAGE open medical case reports
A1  - El Tahir, Mohamed
A1  - Ahmed, Mai
A1  - Salman, Salma
A1  - Elhusein, Bushra
SP  - e2050313X221103355
EP  - e2050313X221103355
VL  - 10
IS  - 
N2  - Dandy-Walker malformation is a group of brain malformations that sometimes present with psychotic features, violent and impulsive behavior, or mood symptoms. Here, we present a case report of a patient with Dandy-Walker malformation who presented with intermittent explosive disorder. A young man, aged 18 years, was brought to the author's hospital [Hamad Medical Corporation] with anger outbursts, irritable mood, and violent behavior. His magnetic resonance imaging scans showed typical alterations of Dandy-Walker malformation. He also had mild intellectual disabilities and epilepsy. After a few weeks of treatment with sodium valproate 1000 mg/day and risperidone 2 mg/day, his condition improved, and his violent behavior was significantly reduced in 3 months, 6 months, and 1 year of follow-up. There is broad consensus that Dandy-Walker malformation is associated with psychosis and other behavioral abnormalities because of a possible disruption in the prefrontal, thalamic, and cerebellar circuits. The link between Dandy-Walker malformation and intermittent explosive disorder may help us understand this type of brain malformation as a potential psychiatric comorbidity.<p />  <p>Language: en</p>
LA  - en
SN  - 2050-313X
UR  - http://dx.doi.org/10.1177/2050313X221103355
ID  - ref1
ER  -