TY  - JOUR
PY  - 2022//
TI  - Delirium in hospitalised adults with acute burns - a systematic review
JO  - Burns: journal of the International Society for Burn Injuries
A1  - Stanley, Guy Henry Morton
A1  - Barber, Angus Robert James
A1  - O'Brien, Aoife Mary
A1  - Hamill, Cheryl
A1  - Boardman, Glenn
A1  - Frear, Cody C.
A1  - Edgar, Dale W.
A1  - Seymour, Hannah
A1  - Wood, Fiona M.
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - INTRODUCTION: Delirium is a potentially modifiable, acutely altered mental state, commonly characterised as a hospital-acquired complication. Studies of adult inpatients with acute burns with and without delirium identify causative risks related to the injury or treatment and outcomes related to the patient and healthcare system. We compare patients with and without delirium, providing a high-level quantitative synthesis of delirium risks and outcomes to inform guidelines and future research. <br><br>METHODS: A systematic review, meta-analysis and GRADE evaluation of risks and outcomes associated with delirium in adults with acute burns was conducted using PRISMA guidelines and PROSPERO protocol CRD42021283055. The Newcastle-Ottawa Scale was used to assess quality. <br><br>RESULTS: Investigators reviewed ten studies. ASA score ≥ 3, Total Body Surface Area Percentage (TBSA)> 10%, surgery done, ICU admission, hospital and also Intensive Care Unit (ICU) lengths of stay all had statistically significant associations with delirium, with low-very low certainty on GRADE evaluation. Limitations were heterogeneous studies, review methodology and study bias. <br><br>CONCLUSION: Delirium represents a significant risk to comorbid patients with burns that are hospitalised, receive ICU care, and surgery. Further research is indicated to precisely categorise delirium along the clinical journey to identify modifiable factors, prevention, and proactive therapy.<p />  <p>Language: en</p>
LA  - en
SN  - 0305-4179
UR  - http://dx.doi.org/10.1016/j.burns.2022.05.023
ID  - ref1
ER  -