TY - JOUR PY - 2022// TI - Carfentanil blood concentrations in impaired driving investigations in Ontario, Canada JO - Journal of analytical toxicology A1 - Wallage, H. Rachelle A1 - Elliot, Marie A1 - Rajotte, James W. SP - ePub EP - ePub VL - ePub IS - ePub N2 - Carfentanil is a potent opioid with no medical use in humans; it presents a serious threat to public health and road safety due to its presence in the illicit drug supply, potency of the drug and instances of use prior to the operation of a motor vehicle. The identification and quantitation of carfentanil using liquid chromatography tandem mass spectrometry was performed in blood samples obtained through impaired driving-related investigations from 2017 to 2019. In a series of 66 cases submitted to the Centre of Forensic Sciences in Ontario, Canada, blood concentrations of carfentanil ranged from less than 0.04 to 2.1 ng/mL in the population studied. Driving behaviors frequently came to the attention of concerned citizens, decreased levels of consciousness were commonly reported and a variety of medical interventions were required, in some cases, to preserve life due to apparent opioid toxicity. Keywords: Drug impaired driving
Language: en
LA - en SN - 0146-4760 UR - http://dx.doi.org/10.1093/jat/bkac039 ID - ref1 ER -