TY  - JOUR
PY  - 2022//
TI  - Intracerebral mechanisms explaining the impact of incidental feedback on mood state and risky choice
JO  - Elife
A1  - Cecchi, Romane
A1  - Vinckier, Fabien
A1  - Hammer, Jiri
A1  - Marusic, Petr
A1  - Nica, Anca
A1  - Rheims, Sylvain
A1  - Trebuchon, Agnès
A1  - Barbeau, Emmanuel J.
A1  - Denuelle, Marie
A1  - Maillard, Louis
A1  - Minotti, Lorella
A1  - Kahane, Philippe
A1  - Pessiglione, Mathias
A1  - Bastin, Julien
SP  - e72440
EP  - e72440
VL  - 11
IS  - 
N2  - Identifying factors whose fluctuations are associated with choice inconsistency is a major issue for rational decision theory. Here, we investigated the neuro-computational mechanisms through which mood fluctuations may bias human choice behavior. Intracerebral EEG data were collected in a large group of subjects (n = 30), while they were performing interleaved quiz and choice tasks that were designed to examine how a series of unrelated feedbacks affects decisions between safe and risky options. Neural baseline activity preceding choice onset was confronted first to mood level, estimated by a computational model integrating the feedbacks received in the quiz task, and then to the weighting of option attributes, in a computational model predicting risk attitude in the choice task. <br><br>RESULTS showed that 1) elevated broadband gamma activity (BGA) in the ventromedial prefrontal cortex (vmPFC) and dorsal anterior insula (daIns) was respectively signaling periods of high and low mood, 2) increased vmPFC and daIns BGA respectively promoted and tempered risk taking by overweighting gain versus loss prospects. Thus, incidental feedbacks induce brain states that correspond to different moods and bias the evaluation of risky options. More generally, these findings might explain why people experiencing positive (or negative) outcome in some part of their life tend to expect success (or failure) in any other.<p />  <p>Language: en</p>
LA  - en
SN  - 2050-084X
UR  - http://dx.doi.org/10.7554/eLife.72440
ID  - ref1
ER  -