TY  - JOUR
PY  - 2022//
TI  - Functional neuro-anatomy of social cognition in posttraumatic stress disorder: a systematic review
JO  - Psychiatry research
A1  - Couette, Maryline
A1  - Mouchabac, Stephane
A1  - Adrien, Vladimir
A1  - Cagnone, Vanessa
A1  - Bourla, Alexis
A1  - Ferreri, Florian
SP  - e114729
EP  - e114729
VL  - 315
IS  - 
N2  - OBJECTIVE  Post-traumatic stress disorder (PTSD) is a common mental disorder following one or more traumatic events in which patients exhibit behavioural and emotional disturbances. Recent studies report alterations in social cognition with cerebral functioning modifications. While it is now established that brain function can be modified and severely altered following successive childhood traumas, less studies have focused on brain alterations in adults with normal social cognition development.     Methods  We conducted a selective literature review by querying PubMed and Embase databases for titles of articles research on PTSD adults published from January 2000 to December 2021 focusing on adulthood traumatic events.     Results  Majority of studies reported frontolimbic rupture, with limbic structures like amygdala missing top-down control of frontal regulation. These cerebral dysfunctions could be observed even without overt behavioural defects on social cognition tests.     Conclusion  These results can be analysed in light of intrinsic cerebral networks and we propose an attentional model of social threat information processing opening up perspective of social attentional rehabilitation in adjunction to usual care.<p />  <p>Language: en</p>
LA  - en
SN  - 0165-1781
UR  - http://dx.doi.org/10.1016/j.psychres.2022.114729
ID  - ref1
ER  -