TY  - JOUR
PY  - 2022//
TI  - Predictive modeling for suicide-related outcomes and risk factors among patients with pain conditions: a systematic review
JO  - Journal of clinical medicine
A1  - Huang, Shu
A1  - Lewis, Motomori O.
A1  - Bao, Yuhua
A1  - Adekkanattu, Prakash
A1  - Adkins, Lauren E.
A1  - Banerjee, Samprit
A1  - Bian, Jiang
A1  - Gellad, Walid F.
A1  - Goodin, Amie J.
A1  - Luo, Yuan
A1  - Fairless, Jill A.
A1  - Walunas, Theresa L.
A1  - Wilson, Debbie L.
A1  - Wu, Yonghui
A1  - Yin, Pengfei
A1  - Oslin, David W.
A1  - Pathak, Jyotishman
A1  - Lo-Ciganic, Wei-Hsuan
SP  - e4813
EP  - e4813
VL  - 11
IS  - 16
N2  - Suicide is a leading cause of death in the US. Patients with pain conditions have higher suicidal risks. In a systematic review searching observational studies from multiple sources (e.g., MEDLINE) from 1 January 2000-12 September 2020, we evaluated existing suicide prediction models' (SPMs) performance and identified risk factors and their derived data sources among patients with pain conditions. The suicide-related outcomes included suicidal ideation, suicide attempts, suicide deaths, and suicide behaviors. Among the 87 studies included (with 8 SPM studies), 107 suicide risk factors (grouped into 27 categories) were identified. The most frequently occurring risk factor category was depression and their severity (33%). Approximately 20% of the risk factor categories would require identification from data sources beyond structured data (e.g., clinical notes). For 8 SPM studies (only 2 performing validation), the reported prediction metrics/performance varied: C-statistics (n = 3 studies) ranged 0.67-0.84, overall accuracy(n = 5): 0.78-0.96, sensitivity(n = 2): 0.65-0.91, and positive predictive values(n = 3): 0.01-0.43. Using the modified Quality in Prognosis Studies tool to assess the risk of biases, four SPM studies had moderate-to-high risk of biases. This systematic review identified a comprehensive list of risk factors that may improve predicting suicidal risks for patients with pain conditions. Future studies need to examine reasons for performance variations and SPM's clinical utility.<p />  <p>Language: en</p>
LA  - en
SN  - 2077-0383
UR  - http://dx.doi.org/10.3390/jcm11164813
ID  - ref1
ER  -