TY - JOUR PY - 2022// TI - Neuroendocrine regulation of female aggression JO - Frontiers in endocrinology A1 - Oliveira, Vinícius Elias de Moura A1 - Bakker, Julie SP - e957114 EP - e957114 VL - 13 IS - N2 - Classically the neurobiology of aggression has been studied exclusively in males. Thus, females have been considered mildly aggressive except during lactation. Interestingly, recent studies in rodents and humans have revealed that non-lactating females can show exacerbated and pathological aggression similarly to males. This review provides an overview of recent findings on the neuroendocrine mechanisms regulating aggressive behavior in females. In particular, the focus will be on novel rodent models of exaggerated aggression established in non-lactating females. Among the neuromodulatory systems influencing female aggression, special attention has been given to sex-steroids and sex-steroid-sensitive neuronal populations (i.e., the core nuclei of the neural pathway of aggression) as well as to the neuropeptides oxytocin and vasopressin which are major players in the regulation of social behaviors.

Language: en

LA - en SN - 1664-2392 UR - http://dx.doi.org/10.3389/fendo.2022.957114 ID - ref1 ER -