TY  - JOUR
PY  - 2022//
TI  - Biosignature of self-injury behaviors in adolescence: role of β-endorphin in an acute inpatient unit
JO  - Frontiers in psychiatry
A1  - Wang, Ping
A1  - Li, Chao
A1  - Del Sol-Calderon, Pablo
A1  - Mallol, Leticia
A1  - Hernandez-Alvarez, Elena
A1  - Donoso-Navarro, Encarnación
A1  - Gil-Ligero, María
A1  - Rosado-Garcia, Silvia
A1  - Sánchez-Lòpez, Antonio José
A1  - Martín-Moratinos, Marina
A1  - Bella-Fernández, Marcos
A1  - Blasco-Fontecilla, Hilario
SP  - e933275
EP  - e933275
VL  - 13
IS  - 
N2  - Self-injurious behavior (SIB) (either non-suicidal self-injury, NSSI; or suicide attempts, SA) is a common reason for adolescent psychiatric emergency hospitalizations. Altered basal serum β-endorphin (BE) levels have been reported in adults with a history of SIB, but information is lacking in adolescents. We analyzed the psychoclinical profile and serum BE level of 39 adolescents admitted to the acute unit at a hospital in Spain due to SIB. The Mean (SD) serum BE level was high (190.53 ± 74.83). Regarding time sequence, the onset age of NSSI and SA were related (p < 0.001). The older the onset age of NSSI, the shorter the transition between NSSI and the onset of SA behavior (p = 0.05), but this difference does not lead the variation of BE (p = 0.81). Patients diagnosed with depression had lower serum BE levels than adolescents with other diagnoses (p = 0.03). Although adolescents who seem to be addicted to SIB had higher levels of BE, this finding was not statistically significant. The relationship between serum BE levels and SIB in adolescents requires further investigation.<p />  <p>Language: en</p>
LA  - en
SN  - 1664-0640
UR  - http://dx.doi.org/10.3389/fpsyt.2022.933275
ID  - ref1
ER  -