TY - JOUR PY - 2022// TI - Social determinants of participant recruitment and retention in a prospective cohort study of pediatric mild traumatic brain injury JO - Frontiers in neurology A1 - Wells, Jordee M. A1 - Galarneau, Jean-Michel A1 - Minich, Nori M. A1 - Cohen, Daniel M. A1 - Clinton, Kameron A1 - Taylor, H. Gerry A1 - Bigler, Erin D. A1 - Bacevice, Ann A1 - Mihalov, Leslie K. A1 - Bangert, Barbara A. A1 - Zumberge, Nicholas A. A1 - Yeates, Keith Owen SP - e961024 EP - e961024 VL - 13 IS - N2 - BACKGROUND: Prior studies have shown poor recruitment and retention of minoritized groups in clinical trials.

OBJECTIVE: To examine several social determinants as predictors of consent to participate and retention as part of a prospective, longitudinal cohort study of children 8-16 with either mild traumatic brain injury (mild TBI) or orthopedic injury (OI).

METHODS: Children and families were recruited during acute visits to emergency departments (ED) in two large children's hospitals in the midwestern United States for a prospective, longitudinal cohort study of children 8-16 with either mild TBI or OI.

RESULTS: A total of 588 (mild TBI = 307; OI = 281) eligible children were approached in the ED and 315 (mild TBI = 195; OI = 120) were consented. Children who consented did not differ significantly from those who did not consent in sex or age. Consent rates were higher among Black (60.9%) and multi-racial (76.3%) children than white (45.3%) children. Among the 315 children who consented, 217 returned for a post-acute assessment (mild TBI = 143; OI = 74), a retention rate of 68.9%. Participants who were multi-racial (96.6%) or white (79.8%) were more likely to return for the post-acute visit than those who were Black (54.3%).

CONCLUSIONS: Racial differences exist in both recruitment and retention of participants in a prospective, longitudinal cohort of children with mild TBI or OI. Further work is needed to understand these differences to ensure equitable participation of minoritized groups in brain injury research.

Language: en

LA - en SN - 1664-2295 UR - http://dx.doi.org/10.3389/fneur.2022.961024 ID - ref1 ER -