TY  - JOUR
PY  - 2022//
TI  - A systematic review and meta-analysis of suicidality in psychotic disorders: stratified analyses by psychotic subtypes, clinical setting and geographical region
JO  - Neuroscience and biobehavioral reviews
A1  - Álvarez, Aida
A1  - Guàrdia, Armand
A1  - González-Rodríguez, Alexandre
A1  - Betriu, Maria
A1  - Palao, Diego
A1  - Monreal, Jose Antonio
A1  - Soria, Virginia
A1  - Labad, Javier
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - We studied the prevalence of suicide attempts and cumulative incidence of completed suicide in schizophrenia (SZ), schizoaffective disorder (SZAF), delusional disorder (DD) and first-episode psychosis (FEP). A systematic review was performed using Scopus and PubMed databases (1990- July 2020). A random effects meta-analysis was conducted. Stratified analyses were conducted by diagnosis, clinical setting and geographical region. The prevalence of attempted suicide was 20.3% for SZ, 46.8% for SZAF, 11.1% for DD and 12.5% for FEP. Suicide attempts rates were higher for outpatient samples than for inpatient samples in SZ, SZAF and DD (but not FEP) studies. Analyses by geographical region in SZ showed greater prevalence of suicide attempts in North America and Northern Europe. The cumulative incidence of completed suicide was 2.0% for SZ, 2.4% for SZAF; 2.2% for DD and 1.9% for FEP. In schizophrenia and FEP studies, Northern European studies reported higher rates of completed suicide when compared to Western European countries. In conclusion, suicidal behaviour rates in psychoses differ by diagnoses, clinical setting and geographical region.<p />  <p>Language: en</p>
LA  - en
SN  - 0149-7634
UR  - http://dx.doi.org/10.1016/j.neubiorev.2022.104964
ID  - ref1
ER  -