TY  - JOUR
PY  - 2022//
TI  - Association between traumatic brain injury and suicidality using a mediation approach and MarketScan
JO  - Injury prevention
A1  - Miller, Gabrielle F.
A1  - Zhou, Hong
A1  - Peterson, Alexis B.
A1  - Swedo, Elizabeth
A1  - Holland, Kristin
A1  - Kresnow, Marcie-jo
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - INTRODUCTION: Negative outcomes, including suicidal ideation/attempts, are a major public health concern, particularly among individuals who sustain a traumatic brain injury (TBI). TBI is associated with high rates of postinjury substance use, psychiatric disorders, post-traumatic stress disorder and sleep disturbances. This study examines the mediation effects of substance use, psychiatric disorder and sleep disorder on the associations between TBI and suicidal ideation/attempts. <br><br>METHODS: A matched case-control study using data from MarketScan databases for private health insurance and Medicaid from October 2015 to December 2018 estimated the association between TBI and suicidal ideation/attempts using a mediation approach. Individuals less than 65 years of age were included. <br><br>RESULTS: In the Medicaid sample, psychiatric disorders mediated 22.4% of the total effect between TBI and suicidal ideation/attempt, while substance use disorders other than opioid use disorder mediated 7.47%. In the private health insurance sample, psychiatric disorders mediated 3.97% of the total effect, opioid use disorders mediated 2.08% of the total effect and sleep disorder mediated 1.25% of the total effect. <br><br>CONCLUSIONS: Mediators explained less than 30% of the relationship between TBI and suicidal ideation/attempt. <br><br>FINDINGS reinforce the importance of primary prevention of TBI and monitoring patients with a TBI for risk of suicide in the first 6-12 months following injury.<p />  <p>Language: en</p>
LA  - en
SN  - 1353-8047
UR  - http://dx.doi.org/10.1136/ip-2022-044697
ID  - ref1
ER  -