TY  - JOUR
PY  - 2023//
TI  - Severe copper sulphate poisoning: a case rescued with plasmapheresis
JO  - Tropical doctor
A1  - Shankar, Jandhyala Anand
A1  - Kaur, Anterpreet
A1  - Tyagi, Lakshay
A1  - Selvam, Suresh
A1  - Hans, Rekha
A1  - Pannu, Ashok Kumar
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - Acute copper sulphate poisoning is associated with multi-organ failure and high mortality. Patients typically present with gastrointestinal symptoms, haemolysis, methaemoglobinaemia, acute liver injury, rhabdomyolysis and renal failure. Management is usually supportive, and the role of chelation therapy has not been established. Copper is not dialysable. Plasmapheresis has been shown to remove protein-bound copper, reducing plasma and intracellular concentrations. We present a case of severe copper sulphate poisoning, who did not improve with chelation therapy with D-penicillamine and supportive care, but with therapeutic plasma exchange (four cycles) showed rapid clinical recovery.<p />  <p>Language: en</p>
LA  - en
SN  - 0049-4755
UR  - http://dx.doi.org/10.1177/00494755231151256
ID  - ref1
ER  -