TY - JOUR PY - 2023// TI - Self-report and urine drug screen concordance among women with co-occurring PTSD and substance use disorders participating in a clinical trial: impact of drug type and participant characteristics JO - Drug and alcohol dependence A1 - Ruglass, L. M. A1 - Shevorykin, A. A1 - Zhao, Y. A1 - Killeen, T. K. A1 - Bauer, A. G. A1 - Morgan-López, A. A. A1 - Back, S. E. A1 - Fitzpatrick, S. A1 - López-Castro, T. A1 - Norman, S. B. A1 - Saavedra, L. M. A1 - Hien, D. A. SP - e109769 EP - e109769 VL - 244 IS - N2 - BACKGROUND: Self-report measures are important in substance use assessment, yet they are susceptible to reporting errors. Urine drug screens (UDS) are often considered a more valid alternative. However, collecting in-person UDS may not always be feasible, contributing to the need to understand factors that influence the validity of self-reported substance use.

METHODS: In this secondary analysis of data from 295 women with co-occurring PTSD and substance use disorders (SUD) who participated in a clinical trial testing behavioral interventions, we examined concordance and discordance between self-reported drug use and associated UDS results. Generalized linear mixed models were used to examine the impact of treatment type and participant characteristics on the associations between self-reported drug use and UDS results.

RESULTS: Findings revealed higher disagreement between self-report and UDS for opioids and sedatives (ranging from.77 to.90) and lower disagreement rates for cannabis and cocaine (ranging from.26 to.33). Treatment type was not a significant moderator of the associations between self-report and UDS across all drugs. Among those with a positive opioid UDS, those who reported employment in the past three years were more likely to self-report no opioid use compared to their counterparts without employment in the past three years.

CONCLUSIONS: Findings add to the literature that supports the validity of self-reported cannabis and cocaine use. The greater discrepancies between self-report and UDS test results of opioids and sedatives suggest adjunctive UDS may be required, although a variety of factors other than inaccurate self-report may be associated with this discrepancy.

Language: en

LA - en SN - 0376-8716 UR - http://dx.doi.org/10.1016/j.drugalcdep.2023.109769 ID - ref1 ER -