TY  - JOUR
PY  - 2022//
TI  - Anticipating unipolar depression and bipolar depression in young adult with first episode of depression using childhood trauma and personality
JO  - Frontiers in public health
A1  - Liu, Jiali
A1  - Wang, Yuanyuan
A1  - Wilson, Amanda
A1  - Chen, Hui
A1  - Liu, Peiqu
A1  - Chen, Xianliang
A1  - Tang, Huajia
A1  - Luo, Chenyuli
A1  - Tian, Yusheng
A1  - Wang, Xiaoping
A1  - Cao, Xia
A1  - Zhou, Jiansong
SP  - e1061894
EP  - e1061894
VL  - 10
IS  - 
N2  - OBJECTIVE: Relevant research focusing on young adults with Unipolar Depression (UD) and Bipolar Depression (BD) is limited. The current research aims to investigate childhood trauma and personality traits in young adults with UD and BD. <br><br>METHODS: Two hundred and thirty-five patients in a first depressive episode (diagnosed UD and BD), 16-25 years old, were recruited from Second Xiangya Hospital. And 79 healthy controls (HC) were recruited from the community to form the comparison group. Patients' childhood trauma was measured by the Childhood Trauma Questionnaire (CTQ), and personality was measured by Eysenck Personality Inventory (EPI). The Kruskal-Wallis test was used to compare depression, anxiety, CTQ, and EPI scores between the HC (n = 79), UD (n = 131), and BD (n = 104) groups. Factors independently associated with mood disorders and BD were determined using binary logistic regression analyses. <br><br>RESULTS: Compared with HC, mood disorders had more severe anxiety and depression symptoms, and higher CTQ. Emotional abuse (OR = 1.47; 95% CI = 1.08-2.01), emotional neglect (OR = 1.24; 95% CI = 1.05-1.46), and neuroticism (OR = 1.25; 95% CI = 1.16-1.35) were associated with significantly increased odds of mood disorders. Whereas, higher extraversion scores were a protective factor for mood disorders. Compared with UD, BD had more severe anxiety symptoms, and higher CTQ, than extraversion and neuroticism personality scores. Anxiety (OR = 1.06; 95% CI = 1.02-1.08) and extraversion (OR = 1.05; 95% CI = 1.03-1.09) were associated with significantly increased odds of BD. <br><br>CONCLUSION: Interventions to prevent childhood trauma may improve young adults' mental health. Using childhood trauma and personality to anticipate BD and UD creates more accurate treatment for young adults with first depression.<p />  <p>Language: en</p>
LA  - en
SN  - 2296-2565
UR  - http://dx.doi.org/10.3389/fpubh.2022.1061894
ID  - ref1
ER  -