TY - JOUR
PY - 2023//
TI - Epidemiology of mental health comorbidity in patients with psoriasis: an analysis of trends from 1986 to 2019
JO - Psychiatry research
A1 - Liu, Liu
A1 - Lin, Nai-Xuan
A1 - Yu, Yuan-Ting
A1 - Wang, Si-Han
A1 - Wang, Jiao
A1 - Cai, Xiao-Ce
A1 - Wang, Chun-Xiao
A1 - Zhang, Miao
A1 - Li, Xin
A1 - Li, Bin
SP - e115078
EP - e115078
VL - 321
IS -
N2 - BACKGROUND: The prevalence of mental disorders such as depression, anxiety, and suicide has increased in patients with psoriasis, although no study has systematically analyzed the epidemiology worldwide.
OBJECTIVE: To explore the prevalence and incidence of psoriasis with comorbid mental disorders (i.e., depression, anxiety, and suicide).
METHODS: Five databases from establishment through May 2022 were searched. Stata SE 15.1 was used for the data analysis. Subgroup, meta-regression, and sensitivity analyses were used to evaluate the heterogeneity of pooled studies.
RESULTS: We evaluated 56 studies in our research. The prevalence of depression, anxiety, and suicide in adults with psoriasis was 20%, 21%, and 0.77%. Patients with psoriasis in North America had a higher prevalence of depression and suicide, whereas those in South America had a higher prevalence of anxiety. The incidence of depression, anxiety, and suicide was 42.1, 24.7, and 2.6 per 1000 person-years in adults with psoriasis, respectively. LIMITATIONS: All of the included studies were published in Chinese and English, causing a degree of selection bias.
CONCLUSION: These findings demonstrate the incidence and prevalence of comorbid mental disorders in patients with psoriasis, which may raise awareness among physicians and patients regarding the mental problems associated with psoriasis.
Language: en
LA - en SN - 0165-1781 UR - http://dx.doi.org/10.1016/j.psychres.2023.115078 ID - ref1 ER -