TY  - JOUR
PY  - 2022//
TI  - How does gender-affirming hormone therapy affect QOL in transgender patients?
JO  - Journal of family practice
A1  - Wilhelm, Sarah
A1  - Kelsberg, Gary
A1  - Safranek, Sarah
SP  - 442
EP  - 444
VL  - 71
IS  - 10
N2  - There are modest effects on depression but not anxiety. Gender-affirming hormone therapy (GAHT) is associated with modest improvements in standardized scores for quality of life (QOL) and depression in adult male-to-female and female-to-male transgender people and modest improvements in depression scores in transgender adolescents, but the effect on anxiety is uncertain (strength of recommendation [SOR]: B, based on a preponderance of low-quality prospective cohort studies with inconsistent results). GAHT is associated with reduced gender dysphoria and decreased suicidality (SOR: B, based on a prospective cohort study). However, there is insufficient evidence to determine any effect on suicide completion. No studies associated GAHT with worsened QOL, depression, or anxiety scores.<p />  <p>Language: en</p>
LA  - en
SN  - 0094-3509
UR  - http://dx.doi.org/10.12788/jfp.0521
ID  - ref1
ER  -