TY  - JOUR
PY  - 2023//
TI  - New balance capability index as a screening tool for mild cognitive impairment
JO  - BMC geriatrics
A1  - Masuda, Yukari
A1  - Shikama, Akito
A1  - Murayama, Yuki
A1  - Aita, Yuichi
A1  - Takeuchi, Yoshinori
A1  - Kondo, Genta
A1  - Tsubaki, Takumi
A1  - Nakaya, Kensuke
A1  - Arai, Tetsuaki
A1  - Suzuki, Hiroaki
A1  - Suzuki, Yasuhiro
A1  - Shimano, Hitoshi
A1  - Kawakami, Yasushi
A1  - Yahagi, Naoya
A1  - Hada, Yasushi
SP  - e74
EP  - e74
VL  - 23
IS  - 1
N2  - BACKGROUND: Mild cognitive impairment (MCI) is not just a prodrome to dementia, but a very important intervention point to prevent dementia caused by Alzheimer's disease (AD). It has long been known that people with AD have a higher frequency of falls with some gait instability. Recent evidence suggests that vestibular impairment is disproportionately prevalent among individuals with MCI and dementia due to AD. Therefore, we hypothesized that the measurement of balance capability is helpful to identify individuals with MCI. <br><br>METHODS: First, we developed a useful method to evaluate balance capability as well as vestibular function using Nintendo Wii balance board as a stabilometer and foam rubber on it. Then, 49 healthy volunteers aged from 56 to 75 with no clinically apparent cognitive impairment were recruited and the association between their balance capability and cognitive function was examined. Cognitive functions were assessed by MoCA, MMSE, CDR, and TMT-A and -B tests. <br><br>RESULTS: The new balance capability indicator, termed visual dependency index of postural stability (VPS), was highly associated with cognitive impairment assessed by MoCA, and the area under the receiver operating characteristic (ROC) curve was more than 0.8, demonstrating high sensitivity and specificity (app. 80% and 60%, respectively). <br><br>CONCLUSIONS: Early evidence suggests that VPS measured using Nintendo Wii balance board as a stabilometer helps identify individuals with MCI at an early and preclinical stage with high sensitivity, establishing a useful method to screen MCI.<p />  <p>Language: en</p>
LA  - en
SN  - 1471-2318
UR  - http://dx.doi.org/10.1186/s12877-023-03777-6
ID  - ref1
ER  -