TY  - JOUR
PY  - 2023//
TI  - Characteristics of the cervical spine and cervical cord injuries in older adults with cervical ossification of the posterior longitudinal ligament
JO  - Scientific reports
A1  - Okuwaki, Shun
A1  - Funayama, Toru
A1  - Koda, Masao
A1  - Eto, Fumihiko
A1  - Yamaji, Akihiro
A1  - Yokogawa, Noriaki
A1  - Sasagawa, Takeshi
A1  - Ando, Kei
A1  - Nakashima, Hiroaki
A1  - Segi, Naoki
A1  - Watanabe, Kota
A1  - Nori, Satoshi
A1  - Takeda, Kazuki
A1  - Furuya, Takeo
A1  - Yunde, Atsushi
A1  - Nakajima, Hideaki
A1  - Yamada, Tomohiro
A1  - Hasegawa, Tomohiko
A1  - Terashima, Yoshinori
A1  - Hirota, Ryosuke
A1  - Suzuki, Hidenori
A1  - Imajo, Yasuaki
A1  - Ikegami, Shota
A1  - Uehara, Masashi
A1  - Tonomura, Hitoshi
A1  - Sakata, Munehiro
A1  - Hashimoto, Ko
A1  - Onoda, Yoshito
A1  - Kawaguchi, Kenichi
A1  - Haruta, Yohei
A1  - Suzuki, Nobuyuki
A1  - Kato, Kenji
A1  - Uei, Hiroshi
A1  - Sawada, Hirokatsu
A1  - Nakanishi, Kazuo
A1  - Misaki, Kosuke
A1  - Terai, Hidetomi
A1  - Tamai, Koji
A1  - Shirasawa, Eiki
A1  - Inoue, Gen
A1  - Kakutani, Kenichiro
A1  - Kakiuchi, Yuji
A1  - Kiyasu, Katsuhito
A1  - Tominaga, Hiroyuki
A1  - Tokumoto, Hiroto
A1  - Iizuka, Yoichi
A1  - Takasawa, Eiji
A1  - Akeda, Koji
A1  - Takegami, Norihiko
A1  - Funao, Haruki
A1  - Oshima, Yasushi
A1  - Kaito, Takashi
A1  - Sakai, Daisuke
A1  - Yoshii, Toshitaka
A1  - Ohba, Tetsuro
A1  - Otsuki, Bungo
A1  - Seki, Shoji
A1  - Miyazaki, Masashi
A1  - Ishihara, Masayuki
A1  - Okada, Seiji
A1  - Imagama, Shiro
A1  - Kato, Satoshi
SP  - e2689
EP  - e2689
VL  - 13
IS  - 1
N2  - Although the incidence of cervical spinal cord injury (CSCI) with ossification of the posterior longitudinal ligament (OPLL) has increased in older adults, its etiology and neurological outcomes remain unknown. We identified OPLL characteristics and determined whether they influence neurological severity and improvement of CSCI in older patients. This multicenter retrospective cohort study identified 1512 patients aged ≥ 65 years diagnosed with CSCI on admission during 2010-2020. We analyzed CSCI etiology in OPLL patients. We performed propensity score-adjusted analyses to compare neurological outcomes between patients with and without OPLL. Cases were matched based on variables influencing neurological prognosis. The primary neurological outcome was rated according to the American Spine Injury Association (ASIA) impairment scale (AIS) and ASIA motor score (AMS). In 332 OPLL patients, the male-to-female ratio was approximately 4:1. Half of all patients displayed low-energy trauma-induced injury and one-third had CSCI without a bony injury. Propensity score matching created 279 pairs. There was no significant difference in the AIS grade and AMS between patients with and without OPLL during hospitalization, 6 months, and 12 months following injury. OPLL patients tended to exhibit worse neurological findings during injury; nevertheless, OPLL was not associated with poor neurological improvement in older CSCI patients.<p />  <p>Language: en</p>
LA  - en
SN  - 2045-2322
UR  - http://dx.doi.org/10.1038/s41598-023-29877-2
ID  - ref1
ER  -