TY  - JOUR
PY  - 2023//
TI  - Burns: classification, pathophysiology, and treatment: a review
JO  - International journal of molecular sciences
A1  - Żwierełło, Wojciech
A1  - Piorun, Krzysztof
A1  - Skórka-Majewicz, Marta
A1  - Maruszewska, Agnieszka
A1  - Antoniewski, Jacek
A1  - Gutowska, Izabela
SP  - e3749
EP  - e3749
VL  - 24
IS  - 4
N2  - Burns and their treatment are a significant medical problem. The loss of the physical barrier function of the skin opens the door to microbial invasion and can lead to infection. The repair process of the damage caused by the burn is impaired due to the enhanced loss of fluids and minerals through the burn wound, the onset of hypermetabolism with the concomitant disruption of nutrient supply, and derangements in the endocrine system. In addition, the initiated inflammatory and free radical processes drive the progression of oxidative stress, the inhibition of which largely depends on an adequate supply of antioxidants and minerals. Clinical experience and research provide more and more data to make the treatment of patients with thermal injury increasingly effective. The publication discusses disorders occurring in patients after thermal injury and the methods used at various stages of treatment.<p />  <p>Language: en</p>
LA  - en
SN  - 1661-6596
UR  - http://dx.doi.org/10.3390/ijms24043749
ID  - ref1
ER  -