TY - JOUR PY - 2023// TI - Understanding heterogeneity in suicidal thoughts and behaviours and the implications for genetic studies - a commentary on Lannoy et al. (2022) JO - Journal of child psychology and psychiatry A1 - Mirza, Salahudeen A1 - Docherty, Anna R. A1 - Monson, Eric T. A1 - Coon, Hilary A1 - Keeshin, Brooks A1 - Fries, Gabriel R. SP - ePub EP - ePub VL - ePub IS - ePub N2 - Preventing suicidal thoughts and behaviours (STB) among youth is a global public health priority. STB are known to have a heritable basis, and the development of risk for STB likely arises from complex gene-environment interactions across the life course. Lannoy et al. (Journal of Child Psychology and Psychiatry, 63, 2022 and 1164) describe a study in which polygenic risk for suicide attempt, as well as recent negative life events, were related to recent suicidal ideation in adolescents of about 17 years old. Building on this important work, we highlight several critical areas of focus for research in suicide genetics, including problems of measurement, as well as priorities for better uncovering the specific aetiological pathways to STB.
Language: en
LA - en SN - 0021-9630 UR - http://dx.doi.org/10.1111/jcpp.13778 ID - ref1 ER -