TY  - JOUR
PY  - 2023//
TI  - Correlates of gait speed among older adults from six countries: findings from the COSMIC collaboration
JO  - Journals of gerontology. Series A: Biological sciences and medical sciences
A1  - Sprague, Briana N.
A1  - Zhu, Xiaonan
A1  - Rosso, Andrea L.
A1  - Verghese, Joe
A1  - Delbaere, Kim
A1  - Lipnicki, Darren M.
A1  - Sachdev, Perminder S.
A1  - Ng, Tze Pin
A1  - Gwee, Xinyi
A1  - Yap, Keng Bee
A1  - Kim, Ki-Woong
A1  - Han, Ji Won
A1  - Oh, Dae Jong
A1  - Narazaki, Kenji
A1  - Chen, Tao
A1  - Chen, Sanmei
A1  - Brodaty, Henry
A1  - Numbers, Katya
A1  - Kochan, Nicole A.
A1  - Walker, Richard W.
A1  - Paddick, Stella-Maria
A1  - Gureje, Oye
A1  - Ojagbemi, Akin
A1  - Bello, Toyin
A1  - Rosano, Caterina
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - BACKGROUND: Few studies have compared gait speed and its correlates among different ethnogeographic regions. The goals of this study were to describe usual and rapid gait speed, and identify their correlates, across Australia, Asia, and African countries. <br><br>METHODS: We used data from six population-based cohorts of adults 65+ from six countries and three continents (N=6472), with samples ranging from 231 to 1913. All cohorts are members of the Cohort Studies of Memory in an International Consortium (COSMIC) collaboration. We investigated whether clinical (BMI, hypertension, stroke, APOE status), psychological (cognition, mood, general health) and behavioral factors (smoking, drinking, physical activity) correlated with usual (N = 4 cohorts) and rapid gait speed (N = 3 cohorts) similarly across cohorts. Regression models controlled for age, sex, and education, and were sex-stratified. <br><br>RESULTS: Age- and sex-standardized usual gait speed means ranged from 0.61-1.06 m/s and rapid gait speed means ranged from 1.16-1.64 m/s. Lower body mass index and better cognitive function consistently correlated with faster gait speed in all cohorts. Less consistently, not having hypertension and greater physical activity engagement were associated with faster gait speed. Associations with mood, smoking, and drinking were largely non-significant. These patterns were not attenuated by demographics. There was limited evidence that the associations differed by sex except physical activity, where greater intensity was associated with usual gait among men but not women. <br><br>CONCLUSIONS: This study is among the first to describe usual and rapid gait speeds across older adults in Africa, Asia, and Australia.<p />  <p>Language: en</p>
LA  - en
SN  - 1079-5006
UR  - http://dx.doi.org/10.1093/gerona/glad090
ID  - ref1
ER  -