TY  - JOUR
PY  - 2023//
TI  - Comparing prevalence of sarcopenia using twelve sarcopenia definitions in a large multinational European population of community-dwelling older adults
JO  - Journal of nutrition, health, and aging
A1  - Stuck, A. K.
A1  - Tsai, L.-t.
A1  - Freystaetter, G.
A1  - Vellas, B.
A1  - Kanis, J. A.
A1  - Rizzoli, R.
A1  - Kressig, K. S.
A1  - Armbrecht, G.
A1  - Da Silva, J. A. P.
A1  - Dawson-Hughes, B.
A1  - Egli, A.
A1  - Bischoff-Ferrari, H. A.
SP  - 205
EP  - 212
VL  - 27
IS  - 3
N2  - OBJECTIVES: Multinational prevalence data on sarcopenia among generally healthy older adults is limited. The aim of the study was to assess prevalence of sarcopenia in the DO-HEALTH European trial based on twelve current sarcopenia definitions. SETTING AND PARTICIPANTS: This is an analysis of the DO-HEALTH study including 1495 of 2157 community-dwelling participants age 70+ years from Germany, France, Portugal, and Switzerland with complete measurements of the sarcopenia toolbox including muscle mass by DXA, grip strength, and gait speed. MEASUREMENTS: The twelve sarcopenia definitions applied were Asian Working Group on Sarcopenia (AWGS1), AWGS2, Baumgartner, Delmonico, European Working Group on Sarcopenia in Older People (EWGSOP1), EWGSOP2, EWGSOP2-lower extremities, Foundation for the National Institutes of Health (FNIH1), FNIH2, International Working Group on Sarcopenia in Older People (IWGS), Morley, and Sarcopenia Definitions and Outcomes Consortium (SDOC). <br><br>RESULTS: Mean age was 74.9 years (SD 4.4); 63.3% were women. Sarcopenia prevalence ranged between 0.7% using the EWGSOP2 or AWGS2 definition, up to 16.8% using the Delmonico definition. Overall, most sarcopenia definitions, including Delmonico (16.8%), Baumgartner (12.8%), FNIH1(10.5%), IWGS (3.6%), EWGSOP1 (3.4%), SDOC (2.0%), Morley (1.3%), and AWGS1 (1.1%) tended to be higher than the prevalence based on EWGSOP2 (0.7%). In contrast, the definitions AWGS2 (0.7%), EWGSOP2-LE (1.1%), FNIH2 (1.0%) - all based on muscle mass and muscle strength - showed similar lower prevalence as EWGSOP2 (0.7%). Moreover, most sarcopenia definitions did not overlap on identifying sarcopenia on an individual participant-level. <br><br>CONCLUSION: In this multinational European trial of community-dwelling older adults we found major discordances of sarcopenia prevalence both on a population- and on a participant- level between various sarcopenia definitions. Our findings suggest that the concept of sarcopenia may need to be rethought to reliably and validly identify people with impaired muscle health.<p />  <p>Language: en</p>
LA  - en
SN  - 1279-7707
UR  - http://dx.doi.org/10.1007/s12603-023-1888-y
ID  - ref1
ER  -