TY  - JOUR
PY  - 2023//
TI  - The impact of procalcitonin in assessing outcomes in pediatrics severe trauma cases: a three-year experience from a tertiary hospital
JO  - Biomedicine (Taipei)
A1  - Albuali, Waleed H.
SP  - 39
EP  - 45
VL  - 13
IS  - 1
N2  - BACKGROUND: Although procalcitonin levels are raised in patients with systemic inflammation, its usage in pediatric patients, particularly those in the intensive care unit who are most susceptible to sepsis. <br><br>METHODS: It is a retrospective research study that included pediatric patients aged more than two weeks who were brought to the King Fahd Hospital of the University's PICU owing to serious trauma or post-acute postoperative occurrences from January 2017 to December 2019. At 24 h after admission, data such as age, gender, comorbidities, trauma severity as measured by the Injury Severity Score, and PRISM III score were collected. <br><br>RESULTS: Following a surgery abscess, there were a total of 39 (15.9%) deaths. Patients who died during their hospital stay had significantly higher mean levels of biomarkers such as PRISM III, PCT at 24 h, PCT 48-72 h, and PCT at day 5 (p = 0.001). The area under the ROC curve for PCT level 48/72 h was 0.89 (% CI: 0.85-0.93), p = 0.001, indicating that PCT had highly significant predictive validity in predicting in-hospital mortality at the best cutoff point of >1.35 with a high level of accuracy and precision of 82.1% and 82.0%, respectively. <br><br>CONCLUSION: The serum procalcitonin level (PTCL) can help predict the in-hospital prognosis of pediatrics that has had surgery. A combined control system is designed based on PTC expression for the examination of a patient receiving medication over a longer length of time.<p />  <p>Language: en</p>
LA  - en
SN  - 2211-8020
UR  - http://dx.doi.org/10.37796/2211-8039.1388
ID  - ref1
ER  -