TY  - JOUR
PY  - 2023//
TI  - Transdiagnostic association between subjective insomnia and depressive symptoms in major psychiatric disorders
JO  - Frontiers in psychiatry
A1  - Nakajima, Suguru
A1  - Kaneko, Yoshiyuki
A1  - Fujii, Nobukuni
A1  - Kizuki, Jun
A1  - Saitoh, Kaori
A1  - Nagao, Kentaro
A1  - Kawamura, Aoi
A1  - Yoshiike, Takuya
A1  - Kadotani, Hiroshi
A1  - Yamada, Naoto
A1  - Uchiyama, Makoto
A1  - Kuriyama, Kenichi
A1  - Suzuki, Masahiro
SP  - e1114945
EP  - e1114945
VL  - 14
IS  - 
N2  - In psychiatric disorders, comorbid depressive symptoms are associated with clinically important issues such as reduced quality of life, a poor prognosis, and increased suicide risk. Previous studies have found a close relationship between insomnia and depressive symptoms in major depressive disorder (MDD), and that actively improving insomnia heightens the improvement of depressive symptoms. This study aimed to investigate whether the association between insomnia and depressive symptoms is also found in other psychiatric disorders besides MDD. The subjects were 144 patients with MDD (n = 71), schizophrenia (n = 25), bipolar disorder (n = 22), or anxiety disorders (n = 26). Sleep status was assessed subjectively and objectively using the Athens Insomnia Scale (AIS) and sleep electroencephalography (EEG), respectively. Sleep EEG was performed using a portable EEG device. Depressive symptoms were assessed using the Beck Depression Inventory. Subjective insomnia, as defined by the AIS, was associated with depressive symptoms in all disorders. Moreover, in schizophrenia, a relation between depressive symptoms and insomnia was also found by objective sleep assessment methods using sleep EEG. Our findings suggest that the association between subjective insomnia and depressive symptoms is a transdiagnostic feature in major psychiatric disorders. Further studies are needed to clarify whether therapeutic interventions for comorbid insomnia can improve depressive symptoms in major psychiatric disorders, similar to MDD.<p />  <p>Language: en</p>
LA  - en
SN  - 1664-0640
UR  - http://dx.doi.org/10.3389/fpsyt.2023.1114945
ID  - ref1
ER  -