TY  - JOUR
PY  - 2023//
TI  - Differing associations of depersonalization with physiological response during rest and breath-focused mindfulness in a trauma-exposed female population
JO  - Journal of psychiatric research
A1  - Lathan, Emma C.
A1  - Guelfo, Alfonsina
A1  - La Barrie, Dominique L.
A1  - Teer, Andrew
A1  - Powers, Abigail
A1  - Siegle, Greg
A1  - Fani, Negar
SP  - 193
EP  - 199
VL  - 162
IS  - 
N2  - BACKGROUND: Dissociative and posttraumatic stress disorder (PTSD) symptoms are commonly co-occurring responses to psychological trauma. Yet, these two groups of symptoms appear to be related to diverging patterns of physiological response. To date, few studies have examined how specific dissociative symptoms, namely, depersonalization and derealization, relate to skin conductance response (SCR), a marker of autonomic function, within the context of PTSD symptoms. We examined associations among depersonalization, derealization, and SCR during two conditions - resting control and breath-focused mindfulness - in the context of current PTSD symptoms. <br><br>METHODS: Sixty-eight trauma-exposed women (82.4% Black; M(age) = 42.5, SD(age) = 12.1) were recruited from the community for a breath-focused mindfulness study. SCR data were collected during alternating resting control and breath-focused mindfulness conditions. Moderation analyses were conducted to examine relations among dissociative symptoms, SCR, and PTSD for these different conditions. <br><br>RESULTS: Moderation analyses revealed that depersonalization was linked to lower SCR during resting control, B = 0.0005, SE = 0.0002, p = .006, in participants low-to-moderate PTSD symptoms; however, depersonalization was associated with higher SCR during breath-focused mindfulness, B = -0.0006, SE = 0.0003, p = .029, in individuals with similar levels of PTSD symptoms. No significant interaction between derealization and PTSD symptoms on SCR was observed. <br><br>CONCLUSIONS: Depersonalization symptoms may associate with physiological withdrawal during rest, but greater physiological arousal during effortful emotion regulation in individuals with low-to moderate levels of PTSD, which has significant implications for barriers to treatment engagement as well as treatment selection in this population.<p />  <p>Language: en</p>
LA  - en
SN  - 0022-3956
UR  - http://dx.doi.org/10.1016/j.jpsychires.2023.05.028
ID  - ref1
ER  -