TY - JOUR PY - 2023// TI - Clinical correlates of fear of falling in progressive supranuclear palsy and multiple system atrophy JO - European journal of neurology A1 - Martínez-Villota, Viviana A. A1 - Terroba-Chambi, Cinthia A1 - Castillo-Torres, Sergio A. A1 - Rossi, Malco A1 - Merello, Marcelo SP - ePub EP - ePub VL - ePub IS - ePub N2 - BACKGROUND: Clinical correlates of fear of falling (FoF) are scarcely studied in patients with Progressive Supranuclear Palsy (PSP) and Multiple System Atrophy (MSA).

OBJECTIVE: To evaluate the clinical correlates of FoF in PSP and MSA.

METHODS: A cross-sectional study with motor , cognitive and psychiatric assessment and longitudinal evaluation of falls and FoF at 6-month follow-up.

RESULTS: Twenty-one patients with PSP-P, 22 with MSA (13 MSA-P and 9 MSA-C) and 22 healthy controls were evaluated. 76.2% of patients with PSP and 86.4%of patients with MSA had FoF regardless of falls. Berg Balance Scale (p<0.001), Tinetti Mobility Test (p<0.01), Beck Anxiety Inventory (p=0.001) and Beck Depression Inventory-II (p=0.01) correlated with FoF in patients with PSP and MSA, whereas Timed up and Go test (p=0.01) and Starkstein's Apathy Scale only in MSA (p=0.04).

CONCLUSION: Mobility, balance and gait performance as well as anxiety and depression in PSP and MSA, and apathy in MSA were determinants of FoF. These findings underline the importance of a multidisciplinary approach to FoF in neurodegenerative atypical parkinsonism.

Language: en

LA - en SN - 1351-5101 UR - http://dx.doi.org/10.1111/ene.15864 ID - ref1 ER -