TY  - JOUR
PY  - 2023//
TI  - Recent advances of drugs monitoring in oral fluid and comparison with blood
JO  - Clinical chemistry and laboratory medicine
A1  - Casati, Sara
A1  - Binda, Maddalena
A1  - Dongiovanni, Paola
A1  - Meroni, Marica
A1  - D'Amato, Alfonsina
A1  - Roda, Gabriella
A1  - Orioli, Marica
A1  - Fabbro, Massimo Del
A1  - Tartaglia, Gianluca M.
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - The use of alternative matrices in toxicological analyses has been on the rise in clinical and forensic settings. Oral fluid (OF), as non-invasive fluid, has attracted attention in the field of drug screening, both for therapeutic and forensic purposes, as well as for medical diagnosis, clinical management, on-site (real time) doping and for monitoring environmental exposure to toxic substances. A good correlation between OF and blood is now established for drug concentrations. Therefore, OF might be a potential substitute of blood, especially for long-term surveillance (e.g., therapeutic drugs) or to screen a large number of patients, as well as for the development of salivary point-of-care technologies. In this review, we aimed to summarize and critically evaluate the current literature that focused on the comparison of drugs detection in OF and blood specimens.<p />  <p>Language: en</p>
LA  - en
SN  - 1434-6621
UR  - http://dx.doi.org/10.1515/cclm-2023-0343
ID  - ref1
ER  -