TY  - JOUR
PY  - 2023//
TI  - A systematic review of interventions for resuscitation following drowning
JO  - Resuscitation plus
A1  - Bierens, Joost J. L. M.
A1  - Bray, Janet
A1  - Abelairas-Gómez, Cristian
A1  - Barcala-Furelos, Roberto
A1  - Beerman, Stephen
A1  - Claesson, Andreas
A1  - Dunne, Cody
A1  - Fukuda, Tatsuma
A1  - Jayashree, Muralidharan
A1  - T Lagina, Anthony
A1  - Li, Lei
A1  - Mecrow, Tom
A1  - Morgan, Patrick
A1  - Schmidt, Andrew
A1  - Seesink, Jeroen
A1  - Sempsrott, Justin R.
A1  - Szpilman, David
A1  - Thom, Ogilvie
A1  - Tobin, Joshua
A1  - Webber, Jonathon
A1  - Johnson, Samantha
A1  - Perkins, Gavin D.
SP  - e100406
EP  - e100406
VL  - 14
IS  - 
N2  - OBJECTIVES: The International Liaison Committee on Resuscitation, in collaboration with drowning researchers from around the world, aimed to review the evidence addressing seven key resuscitation interventions: 1) immediate versus delayed resuscitation; (2) compression first versus ventilation first strategy; (3) compression-only CPR versus standard CPR (compressions and ventilations); (4) ventilation with and without equipment; (5) oxygen administration prior to hospital arrival; (6) automated external defibrillation first versus cardiopulmonary resuscitation first strategy; (7) public access defibrillation programmes. <br><br>METHODS: The review included studies relating to adults and children who had sustained a cardiac arrest following drowning with control groups and reported patient outcomes. Searches were run from database inception through to April 2023. The following databases were searched Ovid MEDLINE, Pre-Medline, Embase, Cochrane Central Register of Controlled Trials. Risk of bias was assessed using the ROBINS-I tool and the certainty of evidence was assessed using Grading of Recommendations Assessment, Development and Evaluation. The findings are reported as a narrative synthesis. <br><br>RESULTS: Three studies were included for two of the seven interventions (2,451 patients). No randomised controlled trials were identified. A retrospective observational study reported in-water resuscitation with rescue breaths improved patient outcomes compared to delayed resuscitation on land (n = 46 patients, very low certainty of evidence). The two observational studies (n = 2,405 patients), comparing compression-only with standard resuscitation, reported no difference for most outcomes. A statistically higher rate of survival to hospital discharge was reported for the standard resuscitation group in one of these studies (29.7% versus 18.1%, adjusted odds ratio 1.54 (95% confidence interval 1.01-2.36) (very low certainty of evidence). <br><br>CONCLUSION: The key finding of this systematic review is the paucity of evidence, with control groups, to inform treatment guidelines for resuscitation in drowning.<p />  <p>Language: en</p>
LA  - en
SN  - 2666-5204
UR  - http://dx.doi.org/10.1016/j.resplu.2023.100406
ID  - ref1
ER  -