TY - JOUR PY - 2023// TI - Executive functions in non-suicidal self-injury comorbid first-episode and drug-naïve depression among adolescents JO - Psychiatry research A1 - Wang, Yanni A1 - Zhou, Yue A1 - Li, Guohua A1 - Qin, Peiwu A1 - Wang, Jiesi A1 - Qi, Ling A1 - Li, Linling A1 - Wang, Yang A1 - Wang, Jianhong A1 - Li, Junchang A1 - Liang, Zhen A1 - Zhou, Yongjie SP - e115476 EP - e115476 VL - 328 IS - N2 - Executive functions(EFs) may be associated with the emergence of non-suicidal self-injury(NSSI) due to their role as behavior controllers. EFs includes three core cognitive processes: inhibitory control, working memory, and cognitive flexibility(i.e. the ability to selectively alter cognitive strategies to generate appropriate behavior in the changing environment). This study aimed to systematically explore the three core EFs in depressed adolescents with NSSI. The data was obtained from the baseline data of the Chinese adolescent depression Cohort. The adolescents underwent cognitive assessments to yield domain-specific scores in EFs using the Digit Span Backward test(DSB), the Stroop Color-word interference test- color-word condition(Stroop-CW), and the Wisconsin Card Sorting tests(WCST). The significant differences in WCST scores were found between the NSSI group and the non-NSSI group. NSSI frequency was moderately positively correlated with total errors and negatively correlated with the number of categories completed. The number of categories completed in the "≥200″ NSSI frequency group was significantly lower than that in the "≤10″ NSSI group. The current findings suggested that depressed adolescents who had engaged in NSSI have poorer cognitive flexibility performance compared to adolescents without NSSI. As the frequency of NSSI increased, cognitive flexibility might become worse. These results provide evidence of a connection between executive dysfunctions and NSSI in depressed adolescents.
Language: en
LA - en SN - 0165-1781 UR - http://dx.doi.org/10.1016/j.psychres.2023.115476 ID - ref1 ER -