TY  - JOUR
PY  - 2023//
TI  - Skin temperature as a predictor of on-the-road driving performance in people with central disorders of hypersomnolence
JO  - Journal of sleep research
A1  - Vael, Veronique E. C.
A1  - Bijlenga, Denise
A1  - Schinkelshoek, Mink S.
A1  - van der Sluiszen, Nick N. J. J. M.
A1  - Remmerswaal, Aniek
A1  - Overeem, Sebastiaan
A1  - Ramaekers, Johannes G.
A1  - Vermeeren, Annemiek
A1  - Lammers, Gert Jan
A1  - Fronczek, Rolf
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - Excessive daytime sleepiness is the core symptom of central disorders of hypersomnolence (CDH) and can directly impair driving performance. Sleepiness is reflected in relative alterations in distal and proximal skin temperature. Therefore, we examined the predictive value of skin temperature on driving performance. Distal and proximal skin temperature and their gradient (DPG) were continuously measured in 44 participants with narcolepsy type 1, narcolepsy type 2 or idiopathic hypersomnia during a standardised 1-h driving test. Driving performance was defined as the standard deviation of lateral position (SDLP) per 5 km segment (equivalent to 3 min of driving). Distal and proximal skin temperature and DPG measurements were averaged over each segment and changes over segments were calculated. Mixed-effect model analyses showed a strong, quadratic association between proximal skin temperature and SDLP (p < 0.001) and a linear association between DPG and SDLP (p < 0.021). Proximal skin temperature changes over 3 to 15 min were predictive for SDLP. Moreover, SDLP increased over time (0.34 cm/segment, p < 0.001) and was higher in men than in women (3.50 cm, p = 0.012). We conclude that proximal skin temperature is a promising predictor for real-time assessment of driving performance in people with CDH.<p />  <p>Language: en</p>
LA  - en
SN  - 0962-1105
UR  - http://dx.doi.org/10.1111/jsr.14045
ID  - ref1
ER  -