TY - JOUR PY - 2023// TI - Detection of thiocyanate in postmortem blood of a fatal potassium thiocyanate-poisoning patient using gas chromatography-mass spectrometry JO - Journal of analytical toxicology A1 - Kang, Minji A1 - Moon, Sungmin A1 - Kim, Byungjoo A1 - Kim, So-Hyun A1 - Kim, Junghyun A1 - Park, Heejin A1 - Choi, Hyeyoung A1 - Kim, Seongho A1 - Park, Meejung SP - ePub EP - ePub VL - ePub IS - ePub N2 - Thiocyanate is an inorganic compound used in industrial applications. Here, we report a case of suicidal death due to acute thiocyanate overdose. A 44-year-old man who consumed an unknown amount of thiocyanate solution was transferred to the emergency room and died two hours after admission. An autopsy was performed two days after death. General toxicological analysis of blood using gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-tandem mass spectrometry found no drug or alcohol. Quantification using GC-MS post-derivatization with pentafluorobenzyl bromide revealed 2,290 and 1,920 mg/L of thiocyanate in the heart and femoral blood samples, respectively. Thus, the cause of death was attributed to thiocyanate overdose. This study provides useful information for the interpretation of thiocyanate-related fatalities.
Language: en
LA - en SN - 0146-4760 UR - http://dx.doi.org/10.1093/jat/bkad075 ID - ref1 ER -