TY  - JOUR
PY  - 2023//
TI  - Fatal poisoning due to ingestion of boiled oleander leaf extract
JO  - Journal of forensic sciences
A1  - Okuda, Hirozumi
A1  - Fukushima, Hidetada
A1  - Nakatsukasa, Tomoaki
A1  - Yamamoto, Koji
A1  - Kaizaki-Mitsumoto, Asuka
A1  - Numazawa, Satoshi
A1  - Kamijo, Yoshito
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - Nerium oleander is an ornamental evergreen shrub belonging to the family Apocynaceae. The Apocynaceae family includes the attractive evergreen shrub known as oleander. The cardiotoxic glycoside, oleandrin, is present in all portions of the common oleander plant. Oleander consumption can result in deadly situations accidentally or as a suicide attempt. After consuming kettle-boiled oleander leaf extract as part of a suicide attempt, an 80-year-old man was discovered comatose in his home and taken to our emergency room. The patient's heart rate was 30 beats per minute, and he had hypotension. Arterial blood gas analysis revealed remarkable metabolic acidosis and hyperkalemia (K: 7.7 mEq/L). An electrocardiogram showed a wide QRS wave, similar to a sine curve. The patient collapsed following cardiac arrest soon after hospital arrival. Veno-arterial extracorporeal membrane oxygenation was initiated; however, the patient eventually died. The serum level of oleandrin at hospital arrival, subsequently measured by LC-MS/MS, was found to be 33.4 ng/mL, far above the levels reported in previous fatal cases.<p />  <p>Language: en</p>
LA  - en
SN  - 0022-1198
UR  - http://dx.doi.org/10.1111/1556-4029.15393
ID  - ref1
ER  -