TY  - JOUR
PY  - 2023//
TI  - Risk factors for suicidality across psychosis vulnerability spectrum
JO  - Schizophrenia Research
A1  - Stephan, Nils Malte
A1  - van Sprang, Eleonore Dorothée
A1  - Wiebenga, Jasper Xiao Ming
A1  - Dickhoff, Justine
A1  - Schirmbeck, Frederike
A1  - de Haan, Lieuwe
A1  - van Amelsvoort, Therese
A1  - Veling, Wim
A1  - Alizadeh, Behrooz Z.
A1  - Simons, Claudia J. P.
A1  - Heering, Henriette Dorotheé
SP  - 152
EP  - 160
VL  - 261
IS  - 
N2  - BACKGROUND: Suicide is a leading cause of death in individuals with psychotic disorders. Risk factors for suicidality across the psychosis vulnerability spectrum are insufficiently known. <br><br>METHODS: For patients (n = 830), siblings (n = 664) and controls (n = 444), suicidality was assessed by the use of a clinical interview. Multilevel modelling was used to investigate risk factors of suicidality. Lastly, risk factor × familial risk interaction effects were examined. <br><br>RESULTS: Multivariable models revealed a significant relation between suicidality and depressive symptoms across all three groups, and childhood trauma in patients and siblings. The association between suicidality and psychotic-like experiences is more pronounced in siblings compared to controls. <br><br>CONCLUSION: Across the psychosis vulnerability spectrum, depressive symptoms and childhood trauma have been associated with suicidality. Clinicians should pay attention to suicidality in individuals at high familial risk for psychosis with psychotic-like experiences.<p />  <p>Language: en</p>
LA  - en
SN  - 0920-9964
UR  - http://dx.doi.org/10.1016/j.schres.2023.09.021
ID  - ref1
ER  -