TY - JOUR PY - 2023// TI - Locomotive syndrome and depressive symptoms: a cross-sectional study in middle-aged women JO - Modern rheumatology A1 - Kato, Michitaka A1 - Ozaki, Etsuko A1 - Matsui, Daisuke A1 - Nakano, Wataru A1 - Nakano, Satoko A1 - Ono, Sintaro A1 - Kito, Kazuya A1 - Koyama, Teruhide SP - ePub EP - ePub VL - ePub IS - ePub N2 - OBJECTIVE: Evidence for an association between locomotive syndrome (LS) and depression is lacking in middle-aged women. This study aimed to investigate the relationship between LS severity and depressive symptoms in community-dwelling middle-aged women.

METHODS: This cross-sectional study included 1,520 middle-aged women (mean age 52 ± 6 years). LS severity was evaluated using the 25-question Geriatric Locomotive Function Scale (GLFS-25) questionnaire and motor function test. Depressive symptoms were assessed using the Zung self-rating depression scale (SDS). Multiple logistic regression analyses were performed to determine the association between depressive symptoms and LS severity, adjusting for potential confounding factors.

RESULTS: LS severity, as evaluated through both questionnaires and motor function tests, was significantly associated with depressive symptoms (SDS ≥ 40 points) in middle-aged women. The relationship between LS and depressive symptoms was only significant when assessed through the GLFS-25 questionnaire rather than the motor function tests. Additionally, a stepwise association was observed between pain severity, as assessed by the GLFS-25, and the prevalence of depressive symptoms.

CONCLUSIONS: LS severity is significantly associated with depressive symptoms in community-dwelling middle-aged women, suggesting the need for additional mental status assessment in participants with LS and concurrent pain.

Language: en

LA - en SN - 1439-7595 UR - http://dx.doi.org/10.1093/mr/road096 ID - ref1 ER -