TY - JOUR PY - 2023// TI - Surveillance of xylazine use and poisonings is needed-without blind spots JO - Annals of internal medicine A1 - Palamar, Joseph J. A1 - Goldberger, Bruce A. SP - ePub EP - ePub VL - ePub IS - ePub N2 - Xylazine has become a new addition to the quickly evolving drug landscape in the United States. Just as momentum was gained in testing for fentanyl and other new psychoactive substances and the availability of naloxone to treat fentanyl overdoses increased, fentanyl adulterated with xylazine, a legal veterinary tranquilizer, is now further complicating the opioid crisis. Although it appears that xylazine on its own rarely causes death (1, 2), exposure to xylazine mixed into illicitly manufactured fentanyl has been associated with prolonged sedation (not reversible with naloxone) and a steep increase in deaths (1-3). A new narrative review by D'Orazio and...

Language: en

LA - en SN - 0003-4819 UR - http://dx.doi.org/10.7326/M23-2299 ID - ref1 ER -