TY - JOUR PY - 2023// TI - Pesticide exposure or pesticide poisoning and the risk of depression in agricultural populations: a systematic review and meta-analysis JO - Journal of agromedicine A1 - Frengidou, Elisavet A1 - Galanis, Petros A1 - Malesios, Chrisovalantis SP - ePub EP - ePub VL - ePub IS - ePub N2 - Evidence suggests that farm workers represent a high-risk population for the development of depression. The aim of the study was to clarify the association between pesticide exposure/poisoning and depression. The Preferred Reporting Items for Systematic Reviews and Meta-Analysis were conducted in this systematic review and meta-analysis. Relevant studies were included through searching in PubMed, Scopus, Web of Science, ProQuest, CINAHL and pre-print services databases. A total of eight studies were included. A positive but non-significant association was observed between pesticide use and depression (OR = 1.123; 95% CI, 0.932-1.354, p-value = .221) while a significant positive association was observed between pesticide poisoning and depression (OR = 2.942; 95% CI, 1.791-4.831, p-value <.001). The present meta-analysis suggested clearly a significant positive association between pesticide poisoning and depression, confirming the hypothesis that pesticide poisoning is a risk factor of depression. It also revealed positive, yet non-significant association, between pesticide exposure and depression, a finding that enhances recent research but requires to be further supported by future cohort studies, including socioeconomic factors and biomarkers of depression.

Language: en

LA - en SN - 1059-924X UR - http://dx.doi.org/10.1080/1059924X.2023.2278801 ID - ref1 ER -