TY  - JOUR
PY  - 2023//
TI  - Toxoplasma gondii infection of the central nervous system and suicide: a case-control study of decedents
JO  - European journal of microbiology and immunology (Budapest)
A1  - Mendoza-Larios, Laura Alejandra
A1  - Garcia-Dolores, Fernando
A1  - Sánchez-Anguiano, Luis Francisco
A1  - Antuna-Salcido, Elizabeth Irasema
A1  - Hernández-Tinoco, Jesús
A1  - Rocha-Salais, Adriana
A1  - Segoviano-Mendoza, Marcela Araceli
A1  - Sifuentes-Alvarez, Antonio
A1  - Alvarado-Esquivel, Cosme
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - We sought to determine the association between Toxoplasma gondii (T. gondii) infection of the central nervous system and suicide in a sample of decedents in Mexico City. One hundred and forty-seven decedents (87 who committed suicide and 60 who did not commit suicide) were studied. Brain tissues (amygdala and prefrontal cortex) of decedents were examined for the detection of T. gondii using immunohistochemistry. Detection of T. gondii was positive in 7 (8.0%) of the 87 cases (6 found in prefrontal cortex and one in amygdala), and in one (1.7%) of the 60 controls (found in prefrontal cortex) (OR: 5.16; 95% CI: 0.61-43.10; P = 0.14). <br><br>RESULTS suggest that T. gondii infection in brain is not associated with suicide. Further studies to confirm this finding are needed.<p />  <p>Language: en</p>
LA  - en
SN  - 2062-509X
UR  - http://dx.doi.org/10.1556/1886.2023.00033
ID  - ref1
ER  -