TY  - JOUR
PY  - 2023//
TI  - Excessive daytime sleepiness and insomnia symptoms in adolescents with major depressive disorder: prevalence, clinical correlates, and the relationship with psychiatric medications use
JO  - Psychiatry investigation
A1  - Shi, Yudong
A1  - Li, Wei
A1  - Chen, Changhao
A1  - Yuan, Xiaoping
A1  - Yang, Yingying
A1  - Wang, Song
A1  - Liu, Zhiwei
A1  - Geng, Feng
A1  - Wang, Jiawei
A1  - Luo, Xiangfen
A1  - Wen, Xiangwang
A1  - Xia, Lei
A1  - Liu, Huanzhong
SP  - 1018
EP  - 1026
VL  - 20
IS  - 11
N2  - OBJECTIVE: Excessive daytime sleepiness (EDS) and insomnia symptoms are common in patients with major depressive disorder (MDD), which might lead to a poor prognosis and an increased risk of depression relapse. The current study aimed to investigate the prevalence, and sociodemographic and clinical correlates of EDS and insomnia symptoms among adolescents with MDD. <br><br>METHODS: The sample of this cross-sectional study included 297 adolescents (mean age=15.26 years; range=12-18 years; 218 females) with MDD recruited from three general and four psychiatric hospitals in five cities (Hefei, Bengbu, Fuyang, Suzhou, and Ma'anshan) in Anhui Province, China between January and August, 2021. EDS and insomnia symptoms, and clinical severity of depressive symptoms were assessed using Epworth sleepiness scale, Insomnia Severity Index, and Clinical Global Impression-Severity. <br><br>RESULTS: The prevalence of EDS and insomnia symptoms in adolescents with MDD was 39.7% and 38.0%, respectively. Binary logistic regression analyses showed that EDS symptoms were significantly associated with higher body mass index (odds ratio [OR]=1.097, 95% confidence interval [CI]=1.027-1.172), more severe depressive symptoms (OR=1.313, 95% CI=1.028-1.679), and selective serotonin reuptake inhibitors use (OR=2.078, 95% CI=1.199-3.601). And insomnia symptoms were positively associated with female sex (OR=1.955, 95% CI=1.052-3.633), suicide attempts (OR=1.765, 95% CI=1.037-3.005), more severe depressive symptoms (OR=2.031, 95% CI=1.523-2.709), and negatively associated with antipsychotics use (OR=0.433, 95% CI=0.196-0.952). <br><br>CONCLUSION: EDS and insomnia symptoms are common among adolescents with MDD. Considering their negative effects on the clinical prognosis, regular screening and clinical managements should be developed for this patient population.<p />  <p>Language: en</p>
LA  - en
SN  - 1738-3684
UR  - http://dx.doi.org/10.30773/pi.2023.0013
ID  - ref1
ER  -