TY - JOUR PY - 2023// TI - Pain tolerance and threshold in suicide attempters: a systematic review and meta-analysis JO - Psychiatry research A1 - Risch, Nathan A1 - Alacreu-Crespo, Adrián A1 - Khan, Shazma A1 - Caceda, Ricardo A1 - Teismann, Tobias A1 - Rogers, Megan L. A1 - Courtet, Philippe A1 - Olié, Emilie SP - e115618 EP - e115618 VL - 331 IS - N2 - It has been hypothesized that individuals less sensitive to pain could be at higher risk of suicide. However, data on pain sensitivity in suicide attempters (SA) obtained using experimental procedures are heterogeneous. The aim of this systematic review and meta-analysis was to investigate and compare pain tolerance and threshold in SA (patients with lifetime history of suicide attempt), non-attempters (psychiatric controls, PC), and healthy controls (HC). A random effects meta-analysis was used to estimate the standardized mean differences using data from 16 studies that compared physical pain tolerance and threshold in SA and PC or HC. Pain tolerance and threshold were not significantly different in SA and PC. However, pain tolerance, but not threshold, was higher in SA than HC. Our findings do not support the hypothesis of an altered pain perception related as a trait for suicidal vulnerability, but rather suggest altered pain perception related to psychiatric vulnerability.
Language: en
LA - en SN - 0165-1781 UR - http://dx.doi.org/10.1016/j.psychres.2023.115618 ID - ref1 ER -