TY  - JOUR
PY  - 2023//
TI  - Unraveling the link between hypertension and depression in older adults: a meta-analysis
JO  - Frontiers in public health
A1  - Gan, Qingwen
A1  - Yu, Ran
A1  - Lian, Zerong
A1  - Yuan, Yiling
A1  - Li, Yuanping
A1  - Zheng, Lilan
SP  - e1302341
EP  - e1302341
VL  - 11
IS  - 
N2  - OBJECTIVE: To perform a meta-analyses to understand the current status of and risk factors for depression in older adults with hypertension. <br><br>METHODS: Eight electronic databases and two clinical trial registries were searched to identify studies examining the incidence of and risk factors for depression among older adults with hypertension. The databases were searched from inception to June 2023. The included studies were evaluated using the Newcastle-Ottawa scale and the evaluation tool recommended by the Agency for Health care Research and Quality. <br><br>RESULTS: A total of 18 studies with 29,694 patients were included. Meta-analysis results showed that the prevalence of depression in older adults with hypertension was 29%. The risk factors for depression among this population included sex [OR value 95% confidence interval 2.24 (1.32, 3.82)], education level [OR 95% CI 1.79 (1.02, 3.14)], residence [OR 95% CI 1.37 (1.24, 1.52)], comorbidities [OR 95% CI 1.79 (1.69, 1.90)], hypertension classification [OR 95% CI 2.81 (1.79, 4.42)], marital status [OR 95% CI 1.50 (1.33, 1.69)], sleep status [OR 95% CI 2.86 (2.21, 3.69)], activity limitation [OR 95% CI 3.42 (2.84, 4.13)], drinking [OR 95% CI 2.25 (1.58, 3.19)], social support [OR 95% CI 3.26 (2.42, 4.41)], living alone [OR 95% CI 1.79 (1.57, 2.04)], stressful events [OR 95% CI 1.62 (1.39, 1.90)], and course of diseases [OR 95% CI 3.23 (2.10, 4.97)]. <br><br>CONCLUSION: The incidence of depression in older adults with hypertension is high, and there are many risk factors. Clinical health care professionals should intervene early to target the above risk factors to reduce the incidence of depression in older adults with hypertension worldwide. SYSTEMATIC REVIEW REGISTRATION: PROSPERO (york.ac.uk), identifier [CRD42023417106].<p />  <p>Language: en</p>
LA  - en
SN  - 2296-2565
UR  - http://dx.doi.org/10.3389/fpubh.2023.1302341
ID  - ref1
ER  -