TY  - JOUR
PY  - 2003//
TI  - Rapid cycling bipolar disorder after left temporal polar damage
JO  - Brain injury
A1  - Murai, T.
A1  - Fujimoto, Shinsuke
SP  - 355
EP  - 358
VL  - 17
IS  - 4
N2  - The case of a 48-year-old woman with rapid cycling bipolar disorder subsequent to a traumatic brain injury is reported. Both depressive and manic episodes had an average duration of approximately 1 month, alternating without stable euthymic periods. Neuroradiological examinations revealed a circumscribed lesion in the left temporal pole. After 1 year without treatment, psychiatric intervention and pharmacotherapy was initiated. Her mood swings were successfully treated with the co-administration of valproate and lithium. Case reports of rapid cycling bipolar disorder after traumatic brain injury are very rare and this case supports the idea that temporal polar dysfunction is a candidate for the neurobiological basis of rapid cycling bipolar disorder.<p />  <p>Language: en</p>
LA  - en
SN  - 0269-9052
UR  - http://dx.doi.org/
ID  - ref1
ER  -